![]() ![]() ![]() ![]() These compiled findings from multiple independent trials provide the strongest evidence to date that high-resistance IMST evokes clinically significant reductions in SBP and DBP, and increases in PI MAX, in adult men and women. Gains in PI MAX had a modest inverse relation with age (β = −0.20 ± 0.09 P = 0.03) and baseline PI MAX (β = −0.15 ± 0.07 P = 0.04) but not to reductions in SBP or DBP. PI MAX increased with high-resistance IMST and low-resistance sham training, with a greater increase from high-resistance IMST (+20 ± 17 vs. Greater reductions in SBP were associated with older age (β = −0.07 ± 0.03 P = 0.04) and greater reductions in DBP associated with medication-naïve BP (β = −3 ± 1 P = 0.02) and higher initial DBP (β = −0.12 ± 0.05 P = 0.04). Select subject characteristics slightly modified the impact of IMST on BP. IMST ( n = 67) reduced systolic BP (SBP) by 9 ± 6 mmHg ( P 0.05). ![]() Participants were randomized to high-resistance IMST (75% PI MAX) or low-resistance sham (15% PI MAX) training (30 breaths/day, 5–7 days/wk, 6 wk). In a retrospective analysis of five pilot trials, we assessed the BP-lowering effects of high-resistance inspiratory muscle strength training (IMST) in adults aged 18–82 years and the impact of IMST on maximal inspiratory pressure (PI MAX), a gauge of inspiratory muscle strength and independent disease risk factor. Above-normal blood pressure (BP) is a primary risk factor for cardiovascular diseases. ![]()
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